Mutations in the rpoB Gene of Rifampin Resistant Myco-bacterium tuberculosis Isolated in Isfahan by PCR-SSCP
نویسندگان: ثبت نشده
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منابع مشابه
mutations in the rpob gene of rifampin resistant myco-bacterium tuberculosis isolated in isfahan by pcr-sscp
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ABSTRACTTuberculosis is an infectious disease which occurs widely in the world and becomes one of the top 10 causes of death worldwide. Mutations of the RpoB gene cause the resistance of Mycobacterium tuberculosis to rifampicin that contributes to the occurrence of MDR-TB. This study aimed to determine the pattern of rpoB gene polymorphisms in the MDR M. tuberculosis in Semarang, Indonesia. Mos...
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conclusions we concluded from the results that the frequency of emb-resistant m. tuberculosis cases in iran is lower than that of many other regions. the pcr-sscp technique can separate resistant isolates from sensitive isolates. the sequencing results of this study showed mutation in codons 309 and 299 of the embb gene. in none of the resistant isolates, mutation was observed in codon 306. fur...
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عنوان ژورنال
دوره 16 شماره 2
صفحات -
تاریخ انتشار 2005-06-01
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